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Is Methotrexate a cytotoxic drug? Methotrexate is the generic name for the trade drug names Otrexupв„ў, Rasuvo, Rheumatrex and Trexallв„ў. Drug type: Methotrexate is an anti-cancer ("antineoplastic" or " cytotoxic ") chemotherapy drug. This medication is classified as an "antimetabolite."
How does methotrexate work for cancer? Methotrexate is one of a group of chemotherapy drugs called anti metabolites. These stop cells making and repairing DNA. Cancer cells need to make and repair DNA so that they can grow and multiply. Methotrexate also stops some normal cells working properly, causing side effects.
Which drugs are cytotoxic? Cytotoxic drugs or cytostatics (also cytotoxic chemotherapy) are drugs used to destroy cancer cells. Cytotoxic drugs inhibit cell division and in this way cause cancer cells to die. Cytotoxic drugs are transported in the bloodstream throughout the body.
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